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Dr. Croft, Dr. Golde, and colleagues used a method, consisting of thin sections of brain tissue from mice that were kept alive for months in cell culture dishes, to model how tau accumulates and changes in the brain. Their results showed that brain tissue containing the normal, nonpathological versions of tau do not form inclusions. The researchers were surprised to find that these tau inclusions weren’t just static clumps of protein.
In a study of more than 1,200 people, researchers show that individuals with higher levels of saturated fats in their blood are more likely to develop dementia, including Alzheimer’s disease.
BrightFocus Foundation announces $25.3 million in new grants.
Recently, when their groundbreaking genetics discovery was featured on the cover of Nature, the research team thanked BrightFocus for critical early funding that supported their accomplishments.
BrightFocus-funded researchers discover a potential new treatment approach for Alzheimer’s - restoring the function of regulatory T cells (Tregs) to control the body’s immune response and suppress Alzheimer’s-associated brain inflammation.
An interdisciplinary team of Harvard scientists has successfully reprogrammed cells in mice to reverse vision loss from glaucoma, as well as normal (not disease-related) vision loss associated with aging in mouse models.
BrightFocus Foundation today received the inaugural Impact Award from the Medical Technology Enterprise Consortium (MTEC) for its work supporting the scientific development of better treatments for repeated mild traumatic brain injury (mTBI). MTEC is a public-private partnership with the U.S. Department of Defense and key research, advocacy, and corporate organizations.
Press release on a new Alzheimer’s drug which shows promising results to slow disease progression.
MPTF (Motion Picture & Television Fund) and BrightFocus Foundation today announced a special Valentine’s virtual concert featuring acclaimed multi-hyphenate and Grammy-nominated vocalist Seth MacFarlane in support of the two nonprofits working together on research and care around Alzheimer’s disease.
Research suggests that changes to circulation and density of blood vessels in the eye may signal a risk of dementia and can be used as a screening tool for Alzheimer’s disease.
