Research News

Research News

Recent BrightFocus grantees, Vinit B. Mahajan, MD, PhD, and co-investigator Jessica M. Skeie, PhD, of the University of Iowa mapped the location and quantities of some 4,403 different proteins expressed in the retinal pigment epithelium (RPE) and choroid of the healthy human eye. This molecular map now provides clues as to why certain areas of the choroid are more sensitive to certain diseases, as well as where to target therapies and why.

Jul 3, 2015
Research News
Now that the entire human genome, or set of genes, has been mapped and is at our disposal, the promise of gene therapy lies with being able to “edit” genes as they vary from individual to individual in ways that either cause or might be used to prevent a disease. Recently, a Johns Hopkins research team headed by BrightFocus Grantee Don Zack, MD, PhD, announced they’ve improved upon the state-of-the-art tool for manipulating the genome in research settings.
Jul 3, 2015
Research News

There’s been a major discovery from Washington University in St. Louis (WUSTL). In mice studies, researchers have shown that fibroblast growth factor (FGF) proteins, a family of “signaling proteins” involved in tissue formation, can be independently manipulated to bring about desired results in individual organs without disrupting the organism as a whole.

Jul 3, 2015
Diet & Nutrition
A new study suggests that many people with AMD may not be getting their treatment benefits—or their money’s worth—from their ocular vitamins. It turns out that many of the products being marketed may not contain identical ingredient dosages to the AREDS and AREDS2 formulas.
Jul 3, 2015
Research News

BrightFocus Reports the Highlights in Vision Research from ARVO 2014 - May 3, 2014

Jul 2, 2015
Research News
ARVO is made up of 12,750 vision and ophthalmology researchers from more than 80 countries (and growing). They're an eclectic group of clinical and basic researchers, including MDs, PhDs, and other degrees (optometrists, osteopaths, veterinarians, and scientists at the master's and undergraduate levels).
Jul 2, 2015
Research News

Hundreds of vision disease experts came to Washington, D.C. this week for the 2014 Focus on Eye Health National Summit. BrightFocus and other vision advocacy groups help sponsor this annual event, which is organized by Prevent Blindness. Here are excerpts and insights from many of the featured speakers.

Jul 2, 2015
Research News

The week of July 20-24, 2014 brought the International Society for Eye Research (ISER) biennial meeting to U.S. shores. In San Francisco, ISER 2014 drew 800 scientists from 37 countries to hear about the latest in vision research.

Jul 2, 2015
Research News
Thanks to the mammoth worldwide effort to collect genetic information on glaucoma patients, there’s been a major breakthrough with the discovery of several new gene variants associated with severe glaucoma. The latest discoveries double the number of genes found through earlier studies and lend hope that genetic screening can be used to identify and direct treatment for people at highest risk of losing their sight.
Jul 2, 2015
Research News
Scientists have for the first time identified molecules with the potential to block the accumulation of a toxic eye protein that can lead to early onset of glaucoma. Researchers have implicated a mutant form of a protein called myocilin as a possible root cause of this increased eye pressure.
Jul 2, 2015