New Ways to Predict Progression and Treat Glaucoma

A woman receiving eye drops


Currently approved treatments for glaucoma primarily focus on eye pressure. Numerous therapies exist to lower eye pressure effectively; however, the bulk of them (eyedrops and surgeries) require skill and consistency to achieve results.

Easier methods are needed, as well as new therapies to address other underlying causes of glaucoma besides intraocular pressure (IOP).

BrightFocus grantees are working to develop drugs that will lower eye pressure and protect against nerve cell injury and death, and genome editing approaches to restore the function of trabecular meshwork (a spongy tissue that drains fluids from the eye).

In addition, computerized algorithms are being designed to analyze an assortment of biometric data to better predict and track a patient’s risk of progression to vision loss.




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