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Alzheimer's Disease Glossary

Navigating a diagnosis of an age-related disease can be overwhelming, especially with all the new medical terms involved. Whether you're preparing for a doctor’s visit or simply want to better understand an Alzheimer's Disease diagnosis, this glossary serves as a quick reference to help you define and understand commonly used terms.

Acetylcholine

A chemical that transmits messages between nerve cells (neurons) and from the brain to the body. Acetylcholine levels in the brain decline during Alzheimer’s disease compared to normal aging.

Alzheimer’s disease

A progressive, terminal brain disease that has no known cause or cure. Alzheimer’s is the most common form of dementia and can result in memory loss, confusion, and an inability to care for oneself, among other possible symptoms.

Amyloid plaques

Amyloids are protein fragments that can group together and form plaques in the brain. A buildup of these plaques is commonly observed in brains with Alzheimer’s disease.

Amyloid-beta

A small, sticky portion of the amyloid protein that contributes to plaque formation observed in Alzheimer’s disease.

Astrocytes

Brain cells that help eliminate waste and maintain a harmonious environment. They are also involved in damage response, resource recycling, and other functions.

Cognitive impairment

When a person experiences difficulty with learning, memory, concentration, and everyday decision-making.

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