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Alzheimer’s Disease Research

Alzheimer’s Disease Research, a BrightFocus Foundation program, drives innovative research worldwide to defeat Alzheimer’s disease and related dementias. By providing initial funding for highly innovative, experimental research and creative ideas, we spark revolutionary approaches and life-saving breakthroughs for this devastating disease impacting more than 6.7 million Americans aged 65 and older.

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Our Impact: Making a Difference

Alzheimer’s Disease Research currently supports a global portfolio of 112 innovative scientific grants working toward a cure. Our grants are vetted through a rigorous evaluation process by the world’s top scientists and clinicians who serve on our Scientific Review Committee.

112

Active research grants we’re supporting worldwide

369

Scientists currently supported through our grants

$180M+

Invested in Alzheimer’s research grants since inception

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Recent News

News & Breakthroughs

Learn about bold ideas and the latest research advancements to diagnose, slow the progression, treat, and ultimately cure Alzheimer’s.
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A BrightFocus-Funded Non-Invasive Treatment Slows Alzheimer’s Progression in Yearlong Study

Sinaptica Therapeutics unveils breakthrough Phase 2 results for an experimental non-invasive treatment for Alzheimer’s disease.

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Breaking News Dispatch: A Non-Invasive Alzheimer’s Treatment, Early Detection, and More

Get the latest in Alzheimer’s screening and treatments.

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Could Finding and Treating Tiny Blood Clots in the Brain Delay Alzheimer’s?

A BrightFocus-funded scientist is investigating a novel imaging tool that could be used to find treatable blood clots in the brain and slow the progression of Alzheimer’s disease.

Speakers, chairs, and event organizers of BrightFocus Foundation’s 16th annual Alzheimer’s Fast Track.

BrightFocus Workshop Helps Shape Future Alzheimer’s Leaders

Students and senior Alzheimer’s researchers gathered in Chicago for an immersive workshop hosted by BrightFocus Foundation.

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Reduce Your Dementia Risk: Two New Risk Factors Identified

“It’s never too early in life or too late in life to reduce risk for dementia,” says Dr. Quincy Samus, a member of the Lancet Standing Commission on Dementia Prevention, Intervention, and Care. Learn more about two new ways to do so.

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Alzheimer’s Science News: Fall 2024

In this issue: President’s Corner, What’s Next for Alzheimer’s Treatments, Researcher Spotlight: Marta Casquero-Veiga, PhD, and more!

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BrightFocus Foundation Receives $3.2 Million Grant for Alzheimer’s Research

BrightFocus Foundation received a $3.2 million grant from an anonymous foundation to support 12 new Alzheimer’s Disease Research grants.

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Treating the Heart, Protecting the Brain

Can controlling blood pressure curb mid-life Alzheimer’s risk? A BrightFocus-funded scientist investigates.

Two women sitting together on a grassy hill, enjoying a moment of laughter. The woman on the left, with Down syndrome, wears a purple jacket and yellow sweater, while the woman on the right, wearing a green hoodie, smiles warmly. Trees and a soft, overcast sky are visible in the background.

Investment in Alzheimer’s Research Today Will Yield Health Benefits for the Next Generation of Adults With Down Syndrome, New Report Finds

Report shows that boosting research investment into the wellbeing of adults with Down syndrome would improve their quality-of-life outcomes, reduce caregiving costs, and extend the lifespan of adults with Down syndrome by five years.

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Why It Matters

Why Alzheimer’s Disease Research Matters

Our greatest opportunity to find a cure for Alzheimer’s disease lies in research.

Thanks to generous donor support, Alzheimer’s Disease Research has invested more than $180 million in groundbreaking studies aimed at furthering our understanding of the disease.

With our grants, scientists across the globe are exploring and testing thousands of hypotheses regarding the disease’s onset and progression, leading to the creation of improved earlier detection strategies and new treatments.

Our Approach to Research

Alzheimer’s Disease Research takes a 360-degree approach to funding innovative scientific research worldwide to defeat Alzheimer’s disease. We explore the full range of scientific paths–from genetics to biomarkers–to improve treatments and ultimately find a cure.

Our Approach

Zoom In on Dementia & Alzheimer’s

Stay informed about brain health and the latest scientific breakthroughs by joining our live, interactive virtual discussions with renowned research scientists and clinicians.

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Alzheimer’s Treatments

Although there is no cure for Alzheimer’s disease, certain treatments can help control or delay its symptoms, particularly in the early stages of the disease.

Explore Current Treatments

Train Your Brain

Reading and undertaking mental challenges can help strengthen brain connections in older adults. Memory puzzles like Sudoku are one way to challenge yourself.

Play Sudoku
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Resources

We’re here for you.

Explore articles, videos, brochures, and more to help you understand and manage Alzheimer’s symptoms, treatments, and the latest research toward a cure.
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Downloadable Resource

Understanding Alzheimer’s Disease

Alzheimer’s disease affects people’s memories, but it involves far more than simple forgetfulness. Learn more about this devastating disease.

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Downloadable Resource

Dementia and Alzheimer’s Disease: Understanding the Differences

Alzheimer’s disease and dementia are not one and the same. Learn about the differences between Alzheimer’s disease and dementia. 

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Video

Treating Early-Stage Alzheimer’s Disease: Newly Available Treatments and What They Mean for Patients

This hour-long webinar helps caregivers and patients understand newly approved therapies that treat Alzheimer’s itself, not just the symptoms.

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Zoom In on Dementia & Alzheimer's

How Is Dementia Diagnosed?

Alzheimer’s expert Dr. David Holtzman shares insights on the latest diagnostic methods, when and how to seek a diagnosis, and how to navigate the process.

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Expert Information

Concussions, Traumatic Brain Injuries, and Alzheimer’s Risk

Learn what traumatic brain injury is and how it can increase the risk of developing Alzheimer’s disease.

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Zoom In on Dementia & Alzheimer's

The START Study: Testing an Oral Capsule That May Protect Brain Synapses

Listen to lead research scientist Dr. Christopher van Dyck to learn more.

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Zoom In on Dementia & Alzheimer's

Frontotemporal Dementia: Diagnosis, Trials & Treatment

Scientists are rapidly gaining knowledge about the detection, diagnosis and treatment of FTD. Find the latest information and clinical trials for FTD.

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Expert Information

Why Early Detection of Alzheimer’s Matters

Watch a free online presentation to learn about the importance of early detection of Alzheimer’s disease.

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Expert Information

What’s Next for Alzheimer’s Diagnostic Tests?

Learn how Alzheimer’s diagnostic tests, including blood tests, digital tools, and AI could transform early detection and treatment strategies.

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Grants & Scientists

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Apply for a Research Grant

Alzheimer’s Disease Research provides research funds for U.S. domestic and international research proposals pursuing innovative treatments, prevention strategies, and a cure for Alzheimer’s disease.