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Cure in Mind. Cure in Sight.

For more than 50 years, BrightFocus Foundation has catalyzed scientific breakthroughs across diseases of mind and sight that have led to novel treatments, prevention strategies, and diagnostic tools.

A group photo of the BrightFocus Foundation staff standing in front of their office building.

Our Mission

BrightFocus funds exceptional scientific research worldwide to defeat Alzheimer’s disease, macular degeneration, and glaucoma and provides expert information on these heartbreaking diseases.

Two female researchers in the lab.
National Glaucoma Research grant recipient, Yvonne Ou, MD

Building on Over 50 Years of Impact

Our donors fuel the work of scientists who are paving the way toward cures for Alzheimer’s disease, macular degeneration, and glaucoma. Most of our grants support early-stage research, ensuring fresh perspectives are brought to the forefront and offering an increased return on research investment over time through novel discoveries that fuel the field.

Scientist working in lab.
Macular Degeneration Research grant recipient, Yong-Su Kwon, PhD

Funding Discoveries and Breakthroughs

Our funding has helped blaze new trails of discoveries and breakthroughs, supporting distinguished scientists holding two Nobel Prizes, as well as 49 MetLife Foundation Awards, 34 Potamkin Prizes, and many others. Through our Fast Track programs and scientific travel awards, we are investing in the next generation of innovators around the world.

Research Funded by Country

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Nearly $1 million

Invested in research funding since inception.

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1

Countries where we have supported innovative research.

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Scientists supported by BrightFocus grants.

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BrightFocus Programs

Research Programs

Providing initial funding for highly innovative, global research through three specialized programs.

An Alzheimer's Disease Research er

Alzheimer’s Disease Research

Our funded research on Alzheimer’s disease leaves no stone unturned, exploring the full range of scientific paths toward better treatments and, ultimately, a cure.

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Macular Degeneration Research

We accelerate groundbreaking research to better understand the root causes of and prevention strategies for macular degeneration, a leading cause of blindness in people 50 years and older worldwide.

Woman getting eye exam.

National Glaucoma Research

We are one of the world’s premier nonprofit funders of research on glaucoma, the leading cause of blindness worldwide. Our funded researchers are advancing new and innovative ways of detecting, treating, and preventing this “sneak thief of sight.”

Donate Now to Fund Critical Research

Your gift today can help drive innovation in Alzheimer’s, macular degeneration, and glaucoma research. By donating, you’ll support life-changing research and provide valuable resources for those affected by these devastating diseases. Give now to fuel hope and bring us closer to finding cures.

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World-Class Scientific Advisors

BrightFocus’ scientific portfolio is guided by its world-class scientific review committees composed of renowned leaders in their fields who recommend new research opportunities for BrightFocus to advance its mission.

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Our Leadership

Meet our experienced leadership team guiding BrightFocus Foundation’s mission and impact.

Funding Rising Stars

BrightFocus grant recipients have gone on to receive numerous scientific awards, including two Nobel Prizes, three Breakthrough Prizes, and 34 Potamkin Prizes, among countless others.

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News

Recent News & Breakthroughs

Read about the latest research advancements to better understand, slow the progression of, treat, and ultimately cure Alzheimer’s disease, macular degeneration, and glaucoma.
John Penn, PhD and Dale Young.

BrightFocus Foundation Announces Appointment of Two New Board Members

BrightFocus Foundation, a leading nonprofit funder of innovative research to defeat Alzheimer’s disease, macular degeneration, and glaucoma, has appointed John S. Penn, PhD, a renowned vision scientist and professor at Vanderbilt University Medical Center, and Dale Young, chairman and CEO of Summit Financial Group, to its board of directors.

David Lowing

BrightFocus Foundation Appoints David Lowing as Senior Director of Corporate and Foundation Relations

BrightFocus Foundation appoints David Lowing to lead corporate and foundation relations. With nearly 20 years of experience, including roles at Conquer Cancer and CHOP, he will expand partnerships and funding for research on Alzheimer’s, macular degeneration, and glaucoma.

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Could Listening in to Cellular Communication Help Treat Glaucoma?

By unlocking the secrets of how cells communicate, this first-of-its-kind BrightFocus National Glaucoma Research-funded study could help prevent vision loss and restore sight for those living with the disease.

A microscopic image of cultured retinal pigment epithelial cells.
A microscopic image of cultured retinal pigment epithelial cells. Photo Credit: NIH Flickr

Turning Back the Biological Clock on Aged and Injured Eye Cells

A de-aging technique offers hope for halting damage in early macular degeneration.

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A BrightFocus-Funded Non-Invasive Treatment Slows Alzheimer’s Progression in Yearlong Study

Sinaptica Therapeutics unveils breakthrough Phase 2 results for an experimental non-invasive treatment for Alzheimer’s disease.

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Breaking News Dispatch: A Non-Invasive Alzheimer’s Treatment, Early Detection, and More

Get the latest in Alzheimer’s screening and treatments.

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New Research Links Blue Light to Macular Degeneration Risk, Antioxidants May Offer Hope

Blue light ​may​ damage the eyes by causing unstable “free radicals” to form, ​which increases the risk of​ age-related macular degeneration. BrightFocus-funded research offers a potential way to protect the eyes from blue light.

Abstract artwork of a red brain surrounded by vibrant, intertwining blood vessels and neural pathways in red, blue, and pink.

Could Finding and Treating Tiny Blood Clots in the Brain Delay Alzheimer’s?

A BrightFocus-funded scientist is investigating a novel imaging tool that could be used to find treatable blood clots in the brain and slow the progression of Alzheimer’s disease.

Speakers, chairs, and event organizers of BrightFocus Foundation’s 16th annual Alzheimer’s Fast Track.

BrightFocus Workshop Helps Shape Future Alzheimer’s Leaders

Students and senior Alzheimer’s researchers gathered in Chicago for an immersive workshop hosted by BrightFocus Foundation.

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MTEC Impact Award

BrightFocus received the inaugural Impact Award from the Medical Technology Enterprise Consortium, a U.S. Department of Defense public-private partnership. America’s military and veterans who have experienced repeated mild traumatic brain injury are at 2-5 times the risk for Alzheimer’s and other forms of dementia. BrightFocus is working to advance new protections through the scientific development of better treatments.