RobertVassar
PhD
Location
Chicago, IL, USA
Current Organization
Northwestern University
Biography
Dr. Vassar received his Ph.D. in Molecular Genetics and Cell Biology from the University of Chicago in 1992, working in the lab of Dr. Elaine Fuchs modeling epidermal diseases in transgenic mice. He then did his postdoctoral fellowship in the lab of Dr. Richard Axel at Columbia University in New York on the organization of odorant receptors in the olfactory system. Having a desire to study Alzheimer’s disease (his mother died of the disorder), Vassar joined the biotechnology company Amgen in 1996 as a research scientist in the Neuroscience Department, where he discovered the β-secretase enzyme, BACE. After leaving Amgen in 2001, Vassar joined the faculty of the Feinberg School of Medicine, Northwestern University, Chicago, where he is Professor of Cell and Molecular Biology and continues his work on BACE and mechanisms of Alzheimer’s disease pathogenesis.
Vassar is the recipient of two prestigious Alzheimer’s awards: The MetLife Foundation Award (2007) and the Potamkin Prize (2009). Vassar is also a fellow of the American Association for the Advancement of Science and a Dana Alliance for Brain Initiatives member.
Grants
Grants Featuring
Robert Vassar, PhD
Alzheimer's Disease Research
Identifying Therapeutic Targets to Prevent Amyloid Accumulation
Active Dates
July 01, 2023 - June 30, 2025
Principal Investigator
Arun Upadhyay, PhD
Identifying Therapeutic Targets to Prevent Amyloid Accumulation
Active Dates
July 01, 2023 - June 30, 2025
Principal Investigator
Arun Upadhyay, PhD
Alzheimer's Disease Research
Differentiation of Alzheimer's Disease Subgroups Using sAPPβ and sAPPα as Cerebrospinal Fluid Biomarkers of BACE1 Activity
Active Dates
July 01, 2019 - June 30, 2023
Principal Investigator
Justyna Dobrowolska Zakaria
Differentiation of Alzheimer's Disease Subgroups Using sAPPβ and sAPPα as Cerebrospinal Fluid Biomarkers of BACE1 Activity
Active Dates
July 01, 2019 - June 30, 2023
Principal Investigator
Justyna Dobrowolska Zakaria
Alzheimer's Disease Research
Tau-independent Microtubule Defects in Alzheimer’s: Potential New Drug Targets
Active Dates
July 01, 2017 - June 30, 2019
Principal Investigator
Shahrnaz Kemal, PhD
Tau-independent Microtubule Defects in Alzheimer’s: Potential New Drug Targets
Active Dates
July 01, 2017 - June 30, 2019
Principal Investigator
Shahrnaz Kemal, PhD
Alzheimer's Disease Research
Paired Ig-Like Receptor B: A Novel BACE1 Substrate
Active Dates
July 01, 2015 - June 30, 2017
Principal Investigator
Ming-Hsuan Ou-Yang, PhD
Paired Ig-Like Receptor B: A Novel BACE1 Substrate
Active Dates
July 01, 2015 - June 30, 2017
Principal Investigator
Ming-Hsuan Ou-Yang, PhD
Alzheimer's Disease Research
BACE1 and Axon Guidance
Active Dates
July 01, 2012 - June 30, 2016
Principal Investigator
Robert Vassar, PhD
BACE1 and Axon Guidance
Active Dates
July 01, 2012 - June 30, 2016
Principal Investigator
Robert Vassar, PhD