Genetic Risks for AMD in Australians of Northern and Southern European Origin

This study will investigate whether changes in diet can modify the genetic risk of AMD, which is predetermined by genes. To define genetic risk for AMD, the study will genotype AMD cases and controls from a large Australian cohort of participants of Anglo-Celtic and Mediterranean origin.

This study will investigate whether the risk of AMD, which is predetermined by genes, can be modified by changes in diet. The study will genotype AMD cases and controls from a large Australian cohort of Anglo-Celtic and Mediterranean origin participants to define the genetic risk for AMD. They will identify the AMD genes in elderly from this cohort (about 8,000 people), and correlate genetic status of the participants with their dietary history and condition of the retina. This might be the first step towards personalized medical care, based on knowledge of susceptibility to a disease using genetic and other risk factor information.