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Macular Degeneration Research Request for Proposals

Macular Degeneration Research, a BrightFocus Foundation program, provides research funds for U.S. domestic and international researchers pursuing pioneering research leading to greater understanding, prevention, and treatment of age-related macular degeneration.

We are committed to supporting scientists from diverse backgrounds to foster creativity and innovation in addressing complex scientific challenges. We strongly encourage applications from individuals who are from groups underrepresented in the field of age-related macular degeneration research.

Female researcher in the lab.

FY25 Dates & Deadlines

Letter of Intent

Closed

Full Application (by invitation only)

Closed

Letters of intent for FY26 will open in May 2025.

Due to the large volume of proposals received, we no longer accept proposals by mail or e-mail. You must apply online.

How to Apply for a Grant
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About the Awards

Macular Degeneration Research offers three types of awards:

Postdoctoral Fellowship Program

This fellowship program is intended to support young postdoctoral researchers during their final stages of mentored training. The award provides salary support for a young scientist to conduct postdoctoral studies in an established laboratory focused on research contributing to understanding the biological causes and/or new clinical treatment of macular degeneration and should also serve as the basis for the applicant’s independent research career.

  • Proposal Length: Two-page description of the proposed research
  • Award Amount: $100,000 per year (total value $200,000)
  • Duration: 2 years

New Investigator Grant Program

This research grant is intended to support investigators during their early years as an independent investigator involved in studies that have an impact on the causes and/or treatment of macular degeneration.

  • Proposal Length: Two-page description of the proposed research
  • Award Amount: $150,000 per year (total value $450,000)
  • Duration: Up to 3 years
A close-up view of a researcher using a microscope. The person, wearing white gloves, is adjusting a glass slide with a specimen under the microscope's lens

Innovative Research Grants

This program is intended to provide support for high-risk/high-gain age-related macular degeneration research. We hope to attract established investigators to apply for this support, but the aims of the application must contain outside-the-box ideas that are novel in the field. Applicants who are experts in another field are encouraged to apply their talents to proposing innovative research in the macular degeneration field.]

  • Proposal Length: Three-page description of the proposed research
  • Award Amount: $200,000 per year (total value $600,000)
  • Duration: Up to 3 years

Related News

Explore the latest macular degeneration news from our funded scientists and related information.

How an Innovative Night Vision Test Could Enable Earlier Detection of Age-Related Macular Degeneration

A BrightFocus Foundation Macular Degeneration Research grant recipient aims to bridge the gap in available testing for AMD and detect the condition as early as possible.

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BrightFocus Macular Degeneration Research grantee Aparna Lakkaraju, PhD, right, in the lab.

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Possible Stargardt Disease Treatment Shows Promise

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FDA Approves New Dose of Existing Drug to Treat Macular Degeneration

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Second Geographic Atrophy Treatment Receives FDA Approval

Read about Izervay, a new treatment to slow the progression of geographic atrophy that has received full FDA approval.

A cone photoreceptor, filled with red dye, overlaid on an array of other cone terminals (cyan) in the fovea, part of the retina. Photo courtesy of Mrinalini Hoon and Raunak Sinha.
A cone photoreceptor, filled with red dye, overlaid on an array of other cone terminals (cyan) in the fovea, part of the retina. Photo courtesy of Mrinalini Hoon and Raunak Sinha.

Breakthrough Study Creates Lab-Grown Eye Cells to Treat Macular Degeneration

Learn how lab-grown cone photoreceptor cells offer new hope in treating macular degeneration, a leading cause of irreversible vision loss.

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Eating antioxidant-rich foods like leafy greens, berries, and nuts may lower the risk of age-related macular degeneration. Now, researchers have identified an FDA-approved antioxidant that could help prevent the disease in people with certain genetic risk factors.

Unlocking the Power of Antioxidants: New Research Shows Promising Potential for Targeted Treatments for Age-Related Macular Degeneration

Explore antioxidants’ role in treating age-related macular degeneration, paving the way for new, targeted therapies.

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